Change of Liver Stiffness Measurement by Transient Elastography Before and After Antiviral Treatment in Chronic Hepatitis B Patients
| Reference | Patients | Observation period | Baseline liver stiffness (kPa) | Follow-up liver stiffness (kPa) | p-value |
|---|---|---|---|---|---|
| Gou et al.64 (2010) | 74 | 6 month | 16.5 ± 8.9 | 10.5 ± 4.1 | 0.003 |
| Enomoto et al.65 (2010) | 20 | 1 year | 11.2 (7.0–15.2) | 7.8 (5.1–11.9) | 0.009 |
| Kim et al.66 (2010) | 23 | 1 year | 13.7 ± 7.9 | 11.3 ± 5.3 | 0.018 |
| Wong et al.67 (2011) | 71 | 1 year | 8.8 (3.1–26.3) | 6.6 (3.3–18.8) | <0.001 |
| Fung et al.68 (2011) | 58 | Less than 6 month | 7.9 (3.6–34.3) | 6.4 (3.2–26.3) | <0.001 |
| Lim et al.69 (2011) | 62 | 1 year | 15.1 (5.6–75.0) | 8.8 (3.0-33.8) | NR |
| Fung et al.70 (2011) | 110 | 3 year | 7.3 | 6.1 | <0.001 |
| Ogawa et al.71 (2011) | 22 | 3 year | 8.2 (4.2–28.5) | 5.3 (2.5–18.0) | 0.006 |
| Osakabe et al.72 (2011) | 29 | 3 year | 12.9 (6.2–17.9) | 4.7 (3.1–7.9) | 0.006 |
| Yan et al.73 (2013) | 58 | 1 year | 8.8 (3.2–47.3) | 5.5 (2.8–21.5) | NR |
| Kim et al.74 (2013) | 121 | 3 year | 14.3 (9.0–23.5) | 7.3 (5.3–11.8) | <0.001 |