The Korean Journal of Gastroenterology :eISSN 2233-6869 / pISSN 1598-9992

 

Table. 4.

Treatment for GERD

Total GERD diagnosed with endoscopy GERD diagnosed without endoscopy p-valuea p-valueb
ERD NERD
Treatment, n (%)
Total 18,010 1,349 1,552 15,109 0.3916c 0.0002d
Medication 17,806 (98.87) 1,327 (98.37) 1,520 (97.94) 14,959 (99.01)
Non medical treatment 204 (1.13) 22 (1.63) 32 (2.06) 150 (0.99)
Non medical treatment, n (%)
Total 204 22 32 150 0.2882c <0.0001d
Dietary habits for improvement 171 (83.82) 12 (54.55) 22 (68.75) 137 (91.33)
Antireflus surgery 0 (0.00) 0 (0.00) 0 (0.00) 0 (0.00)
Untreated 33 (16.18) 10 (45.45) 10 (31.25) 13 (8.67)
Treatment period (days)g
Total 16,433 1,294 1,470 13,669 0.0206e <0.0001f
Mean±SD 79.85±183.28 88.36±171.67 93.66±203.50 77.55±181.97
Median 21.00 30.00 28.00 19.00
Min, Max 1.00, 1,460.00 1.00, 1,440.00 1.00, 1,419.00 1.00, 1,460.00
Continuation of treatment, n (%)
Total 18,010 1,349 1,552 15,109 0.2940c <0.0001d
Yes 8,105 (45.00) 774 (57.38) 870 (56.06) 6,461 (42.76)
No 8,328 (46.24) 520 (38.55) 600 (38.66) 7,208 (47.71)
Unverifiable 1,577 (8.76) 55 (4.08) 82 (5.28) 1,440 (9.53)
Pattern of symptom change, n (%)
Total 18,010 1,349 1,552 15,109 0.0058c <0.0001d
Unchanged 5,876 (32.63) 287 (21.28) 338 (21.78) 5,251 (34.75)
Improvement 11,831 (65.69) 1,024 (75.91) 1,154 (74.36) 9,653 (63.89)
Symptom aggravation 140 (0.78) 15 (1.11) 7 (0.45) 118 (0.78)
New symptoms occurred 163 (0.91) 23 (1.70) 53 (3.41) 87 (0.58)

ERD, erosive reflux disease; NERD, nonerosive reflux disease; GERD, gastroesophageal reflux disease; SD, standard deviation; Min, minimum; Max, maximum; n (%), number of subjects (percentage of subjects).

aERD vs. NERD: Pearson's chi-square testc, Wilcoxon's rank sum teste. bERD vs. NERD vs. GERD diagnosed with symptoms only: Pearson's chi-square testd, Kruskal-Wallis testf. gTreatment period=End date-Start date+1.

Medications were duplicated.

Korean J Gastroenterol 2023;82:180~189 https://doi.org/10.4166/kjg.2023.032
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