Recommendations for Initial Laboratory Evaluation of Patients with Acute Liver Failure
| CBC with differential count |
| PT, aPTT |
| Liver panel (protein/albumin, ALP/GGT, AST/ALT, total/direct bilirubin) |
| BUN/creatinine, electrolytes |
| Mineral (including phosphorus, ionized calcium & magnesium) |
| Glucose, lipid profile |
| CRP, procalcitonin |
| Amylase, lipase |
| Ammonia (arterial & venous) |
| ABGA with arterial lactate |
| Serum and urine osmolality |
| HBsAg/Ab, HBcAb IgM/IgG |
| HCV Ab, HCV RNA |
| HAV Ab IgM/IgG |
| HEV Ab IgM/IgG, HEV RNA |
| HIV Ab |
| IgM Ab and/or PCR for EBV, CMV, HSV, VZV |
| Antinuclear Ab, IgG, antimitochondrial Ab, anti-LKM, anti-smooth muscle Ab |
| Ceruloplasmin, serum copper, 24 hour urine copper |
| Acetaminophen level |
| Other toxicology screen |
| AFP, factor V assay |
| Blood type – ABO, Rh |
| Urinalysis with microscopy, urine hCG (in female) |
| Cultures – blood, urine, etc. |
CBC, complete blood count; ABGA, arterial blood gas analysis; Ab, antibody; HIV, human immunodeficiency virus; EBV,