The Korean Journal of Gastroenterology :eISSN 2233-6869 / pISSN 1598-9992

 

Table. 1.

Summary of the Reported Cases of Primary Esophageal Melanoma in Korea

Patient No Study Age (years)/Sex Symptoms (duration) Location Endoscopic finding Stage (TNM) Metastasis Treatment Follow up period (months) Outcome
1 Kim et al. (1991)4 28/Female Dysphagia, odynophagia (6 months) Lower Protruding mass with yellowish discoloration IV (NA) LN RT NA NA
2 Park et al. (1997)5 47/Male Dysphagia (3 months) Lower Multiple black pigmented polypoid mass I (T1N0M0) Absent Surgery NA NA
3 Jung et al. (1997)6 58/Male Dysphagia, substernal pain (3 months) Mid Protruding mass with friable mucosa and easy touch bleeding NA NA Surgery 8 Alive
4 Lee et al. (1998)7 60/Male Dysphagia, epigastric discomfort (3 months) Lower Protruding mass with central ulceration IIB (T2N1M0) LN Surgery NA NA
5 Park et al. (1998)8 36/Female Dysphagia, odynophagia (2 months) Mid Protruding mass IIB (T1N1M0) LN Surgery 11 Recurrence (stomach)
6 Lee et al. (1998)9 47/Male Dysphagia (3 months) Lower Black pigmented polypoid mass I (T1N0M0) Absent Surgery 4 Death (liver metastasis)
7 Lee et al. (1998)9 39/Female Dysphagia (6 months) Lower Protruding mass with central ulceration I (T1N0M0) Absent Surgery 4 Alive
8 Lee et al. (2001)10 67/Male Epigastric discomfort, dyspepsia (1 month) Lower Black pigmented polypoid mass I (T1N0M0) Absent Refuse 8 Alive
9 Lee et al. (2007)11 58/Male Dysphagia, substernal discomfort (4 months) Lower Protruding mass IIA (T2N0M0) Absent Surgery 9 Recurrence (brain, liver, lung metastases)
10 Lee et al. (2004)12 46/Male Dysphagia (3 months) Lower Black pigmented polypoid mass with friable mucosa and easy touch bleeding IV (NA) Liver, LN, brain Chemothe rapy + RT 1 Death
11 Park et al. (2006)13 55/Female Dysphagia, weight loss (1 month) Lower Black pigmented polypoid mass IV (NA) LN Surgery 10 NA
12 Lee et al. (2007)14 60/Male Dysphagia, upper abdominal discomfort (3 months) Lower Black pigmented polypoid mass IVA (T3N0M1) LN at the lesser curvature of the stomach Surgery + chemotherapy 35 Alive
13 Lee et al. (2007)14 63/Male Dysphagia, odynophagia (2 months) Lower Protruding mass with friable mucosa and easy touch bleeding IV (NA) LN, lung Chemothe rapy + RT 4 Progression (skin, perirenal, retroperitoneal, inguinal metastases)
14 Kim et al. (2009)15 56/Male Absent Lower Black pigmented and flat lesion I (T1N0M0) Absent Surgery 4 Alive
15 Kang et al. (2009)16 56/Male Epigastric pain (10 days) Lower Multiple black pigmented and flat lesions I (T1N0M0) Absent NA NA NA
16 Kim et al. (2011)17 61/Male Dysphagia (1 month) Mid Black pigmented polypoid mass III (T3N0M0) Absent Surgery + RT 4 Progression (LN, bone metastases)
17 Lee et al. (2015)18 51/Female Epigastric discomfort, belching Mid Multiple black pigmented and flat lesions IA (T1N0M0) Absent Surgery 15 Alive
18 Choi et al. (2018)19 65/Male Absent Lower Multiple black pigmented and flat lesions IA (T1N0M0) Absent Surgery NA NA
19 Present case 1 38/Male Dysphagia, odynophagia (3 months) Mid Black pigmented polypoid mass III (T3N1M0) LN Chemothe rapy 7 Alive
20 Present case 2 59/Male Dysphagia (2 months) Mid Protruding mass IA (T1N0M0) Absent Surgery 13 Progression (lung, pleura, thyroid, bone, peritoneum, LN)
21 Present case 3 66/Male Absent Lower Multiple black pigmented and flat lesions IA (T1N0M0) Absent Surgery 33 Alive
22 Present case 4 61/Male Epigastric pain, dysphagia (2 months) Mid Black pigmented polypoid mass IV (T3N1M1) LN, lung NA NA NA

T, tumor; N, lymph node metastasis; M, distant metastasis; LN, lymph node; RT, radiation therapy; NA, not available.

Korean J Gastroenterol 2022;79:222~227 https://doi.org/10.4166/kjg.2022.031
© Korean J Gastroenterol