The Korean Journal of Gastroenterology :eISSN 2233-6869 / pISSN 1598-9992


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Fig. 3. Microphotographs show (A) an expansile, well-circumscribed tumor arranged in diffuse sheets and infiltrating the liver with broad pushing borders and dense peritumoral lymphoid infiltrate (H&E, ×40). (B) Higher magnification showing the two distinct components comprised a dilated mucin-filled tumor gland on the left with lymphoepithelioma-like carcinoma (LELC) on the right side (H&E, ×100). (C) LELC component comprised of cells arranged in syncytial sheets having prominent intratumoral and peritumoral lymphocytic infiltrate with the formation of many lymphoid follicles. Few dysplastic glands lined by columnar to cuboidal cells with marked nuclear stratification, hyperchromasia, and conspicuous nucleoli are seen at the junction of two components (H&E, ×200). (D) Higher magnification of LELC areas shows tumor cells present in the syncytial sheets. These have moderate eosinophilic cytoplasm indistinct cell boundaries, large vesicular round to oval-shaped nuclei with single large prominent nucleoli (H&E, ×400).
Korean J Gastroenterol 2021;78:188~194
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