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Korean J Gastroenterol  <  Volume 74(2); 2019 <  Articles

Korean J Gastroenterol 2019; 74(2): 87-94  https://doi.org/10.4166/kjg.2019.74.2.87
Nutritional Support for Patients with Pancreatic Cancer
Min Kyu Jung1 ,2
Department of Internal Medicine, School of Medicine, Kyungpook National University1, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kyungpook National University Hospital2, Daegu, Korea
Correspondence to: Min Kyu Jung, Department of Internal Medicine, School of Medicine, Kyungpook National University, 680 Gukchaebosang-ro, Jung-gu, Daegu 41944, Korea. Tel: +82-53-200-5514, Fax: +82-53-426-8773, E-mail: minky1973@knu.ac.kr, ORCID: https://orcid.org/0000-0001-8749-408X
Received: July 17, 2019; Revised: July 29, 2019; Accepted: August 1, 2019; Published online: August 25, 2019.
© The Korean Journal of Gastroenterology. All rights reserved.

This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Pancreatic cancer is the ninth common malignancy in South Korea. It has a dismal prognosis with a 5-year overall survival rate of less than 10%, and pancreatic cancer is associated with cancer cachexia, which is defined as the loss of muscle mass that is not reversible by conventional nutritional support. Cachexia is noted in over 85% of all pancreatic cancer patients and it is strongly related with the disease’s mortality. Nearly 30% of pancreatic cancer deaths are due to cachexia rather than being due to the tumor burden. Therefore, it is crucial to discover the mechanisms behind the development of muscle wasting in pancreatic cancer patients and find novel therapeutics for targeting cachexia. This review deals with the current understanding about the development of cachexia and nutritional support in those patients suffering with pancreatic cancer.
Keywords: Nutritional support; Pancreatic neoplasms; Cachexia


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