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Korean J Gastroenterol  <  Volume 73(6); 2019 <  Articles

Korean J Gastroenterol 2019; 73(6): 360-364  https://doi.org/10.4166/kjg.2019.73.6.360
Drug Induced Liver Injury by Prophylactic Administration of Albendazole
Sang Yi Moon, Yang Hyun Baek and Sung Wook Lee
Division of Gastroenterology, Department of Internal Medicine, Dong-A University Hospital, Busan, Korea
Correspondence to: Sung Wook Lee, Division of Gastroenterology, Department of Internal Medicine, Dong-A University Hospital, 26 Daesingongwon-ro, Seo-gu, Busan 49201, Korea. Tel: +82-51-240-5042, Fax: +82-51-242-5852, E-mail: sunglee@dau.ac.krsunglee@dau.ac.kr, ORCID: https://orcid.org/0000-0001-9243-8488
Received: November 23, 2018; Revised: February 7, 2019; Accepted: February 8, 2019; Published online: June 25, 2019.
© The Korean Journal of Gastroenterology. All rights reserved.

This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Albendazole is used as a typical antiparasitic agent worldwide. The side effects of albendazole may include nausea, vomiting, abdominal pain, dizziness, headache, alopecia, and increased liver enzymes. Mild elevation of the liver enzyme has been reported in more than 10% of cases, but drug induced liver injury was reported to be very rare. A 30-year-old woman visited the Dong-A University Hospital with anorexia, nausea, jaundice, and elevated liver enzyme. For diagnosis, other acute hepatitis etiologies were excluded, but the prophylactic administration of albendazole was verified. This paper introduces a case of drug-induced liver injury through the prophylactic administration of albendazole. Physicians should be aware of severe liver injury as one of the side effects of albendazole.
Keywords: Albendazole; Drug induced liver injury


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