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Korean J Gastroenterol  <  Volume 73(6); 2019 <  Articles

Korean J Gastroenterol 2019; 73(6): 350-354  https://doi.org/10.4166/kjg.2019.73.6.350
Primary Gastric Choriocarcinoma Coexisting with Adenocarcinoma
Joo Hyun Lee, Jeong Kyun Lee and Dong Baek Kang
Department of Surgery, Wonkwang University School of Medicine, Iksan, Korea
Correspondence to: Dong Baek Kang, Department of Surgery, Wonkwang University School of Medicine, 460 Iksan-daero, Iksan 54538, Korea. Tel: +82-63-859-1490, Fax: +82-63-855-2386, E-mail: east1st@wku.ac.kr , ORCID: https://orcid.org/0000-0003-1082-1251
Received: December 19, 2018; Revised: January 12, 2019; Accepted: February 1, 2019; Published online: June 25, 2019.
© The Korean Journal of Gastroenterology. All rights reserved.

This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Choriocarcinoma is an aggressively growing and widely metastasizing tumor that originates from trophoblastic cells. A primary gastric choriocarcinoma (PGC), however, is very rare. A 76-year-old female patient visited the emergency department of Wonkwang University Hospital with abdominal discomfort and melena. Esophagogastroduodenoscopy revealed a huge ulceroinfiltrative mass lesion with blood clots on the boundary between the greater curvature side and the posterior wall side of the stomach lower body. CT showed a 3-cm exophytic mass lesion with heterogeneous enhancement, an ulcer lesion at the posterior wall side of the stomach lower body, and multiple enlarged lymph nodes at the splenic artery and left gastric artery nodal stations. She underwent a radical subtotal gastrectomy with a D2 lymph node dissection. The final diagnosis was PGC coexisting with adenocarcinoma based on the pathology results. This paper reports a rare case of primary gastric choriocarcinoma coexisting with adenocarcinoma and discusses the characteristics of this neoplasm with reference to the literature.
Keywords: Stomach; Choriocarcinoma; Adenocarcinoma; Chorionic gonadotropin

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