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Korean J Gastroenterol  <  Volume 73(3); 2019 <  Articles

Korean J Gastroenterol 2019; 73(3): 177-181  https://doi.org/10.4166/kjg.2019.73.3.177
Benign Gastric Ulcer with Epstein-Barr Virus Infection Mimicking Malignant Gastric Ulcer
Jin Wuk Gwak, Jiwon Yoo , Seong O Suh, Jaeyeon Kim, In Soo Oh and Ji Yoon Bae1
Departments of Internal Medicine and Pathology1, National Police Hospital, Seoul, Korea
Correspondence to: Jiwon Yoo, Department of Internal Medicine, National Police Hospital, 123 Songi-ro, Songpa-gu, Seoul 05715, Korea. Tel: +82-2-3400-1519, Fax: +82-2-3400-1680, E-mail: outis@police.go.kr, ORCID: https://orcid.org/0000-0003-0337-158X
Received: June 7, 2018; Revised: August 9, 2018; Accepted: August 21, 2018; Published online: March 25, 2019.
© The Korean Journal of Gastroenterology. All rights reserved.

This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Epstein-Barr virus (EBV) is the cause of infectious mononucleosis, which is characterized by fever, lymphadenopathy, and sore throat. On the other hand, gastrointestinal symptoms of EBV infection like dyspepsia, abdominal pain are non-specific and rarely encountered, which means it is difficult to diagnose gastric involvement of EBV infection without suspicion. The relation between gastric carcinoma and gastric lymphoma associated with EBV infection is well defined, but relations with other EBV-associated gastrointestinal diseases such as gastritis and peptic ulcer disease have rarely been reported. We report a case of benign gastric ulcer with EBV infection confirmed by endoscopic and histological findings.
Keywords: Epstein-Barr virus infections; Stomach ulcer; Peptic ulcer; In situ hybridization; Helicobacter pylori


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