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Korean J Gastroenterol  <  Volume 72(5); 2018 <  Articles

The Korean Journal of Gastroenterology 2018; 72(5): 229-236  https://doi.org/10.4166/kjg.2018.72.5.229
Diagnosis of Helicobacter pylori Infection
Cheal Wung Huh and Byung-Wook Kim
Division of Gastroenterology, Department of Internal Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
Correspondence to: Byung-Wook Kim
Received: September 9, 2018; Revised: September 17, 2018; Accepted: September 17, 2018; Published online: November 25, 2018.
© The Korean Journal of Gastroenterology. All rights reserved.

Abstract
Accurate diagnosis of Helicobacter pylori (H. pylori) infection is mandatory for the effective management of many gastroduodenal diseases. Currently, various diagnostic methods are available for detecting these infections, and the choice of method should take into account the clinical condition, accessibility, advantage, disadvantage, as well as cost-effectiveness. The diagnostic methods are divided into invasive (endoscopic-based) and non-invasive methods. Non-invasive methods included urea breath test, stool antigen test, serology, and molecular methods. Invasive methods included endoscopic imaging, rapid urease test, histology, culture, and molecular methods. In this article, we provide a review of the currently available options and recent advances of various diagnostic methods.
Keywords: Helicobacter pylori; Diagnosis; Guideline


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