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Korean J Gastroenterol  <  Volume 72(4); 2018 <  Articles

The Korean Journal of Gastroenterology 2018; 72(4): 163-169  https://doi.org/10.4166/kjg.2018.72.4.163
Gender Difference in Functional Gastrointestinal Disorders
Ju Yup Lee and Kyung Sik Park
Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea
Correspondence to: Kyung Sik Park
Received: September 13, 2018; Revised: October 17, 2018; Accepted: October 17, 2018; Published online: October 25, 2018.
© The Korean Journal of Gastroenterology. All rights reserved.

This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Functional gastrointestinal diseases (FGIDs) are known to be influenced more by a lowering of the quality of life, such as mental health and sleep quality, compared to organic diseases. Genetic, microbiological, molecular biological, and social environmental factors are involved in the pathophysiology of FGIDs. In particular, mental factors, such as depression and anxiety, play a major role in the development of FGIDs. The prevalence of most FGIDs is higher in women. Gender needs to be analyzed in patients with FGIDs because it can have a great influence on the onset of FGIDs. Because there are differences in the treatment response according to gender, further research in the development of therapeutic drugs considering this gender difference will be needed, and ultimately it will be possible to lower the prevalence of FGIDs and improve the quality of life of patients.
Keywords: Sex; Gender; Irritable bowel syndrome; Functional gastrointestinal disorders

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