Changes in the CDAI and Its Components 6 Months after Taking
| Initiation | After 3 months | After 6months | p-value |
||||
|---|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | Mean | SD | ||
| CDAI | 40.65 | 53.65 | 37.60 | 47.84 | 32.06 | 50.29 | <0.01 |
| Body weight score |
-5.70 | 17.11 | -6.59 | 18.14 | -8.15 | 19.38 | <0.01 |
| Hematocrit score |
5.50 | 6.12 | 4.64 | 4.64 | 3.94 | 4.63 | <0.01 |
| Number of liquid or very soft stools per week | 2.28 | 5.98 | 3.26 | 7.40 | 2.95 | 6.87 | 0.37 |
| Abdominal pain | 0.15 | 0.44 | 0.18 | 0.46 | 0.17 | 0.46 | 0.61 |
| General well-being | 0.06 | 0.25 | 0.07 | 0.25 | 0.08 | 0.28 | 0.16 |
| Extra-gastrointestinal symptoms | 0 | 0 | 0.01 | 0.10 | 0 | 0 | 1.00 |
| Anti-diarrhea drug | 0.01 | 0.10 | 0.01 | 0.10 | 0.01 | 0.10 | 1.00 |
| Abdominal mass | 0 | 0 | 0 | 0 | 0 | 0 | 1.00 |
CDAI, Crohn’s disease activity index;
aComparing baseline point to the 6-month time-point; b(Ideal body weight-observed body weight)/ideal body weight×100; cExpected hematocrit (men: 47, women: 42)-observed hematocrit.